产品货号：
GS4428
中文名称：
重组人LEC/CCL16
英文名称：
Recombinant Human Liver-Expressed Chemokine/CCL16
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 11.2kDa,a single non-glycosylated polypeptide chain containing 97 amino acids.
储存条件：冷冻（-20℃）
概述
Human CCL16,also called Liver-expressed chemokine(LEC),Monotactin-1(MTN-1),IL-10-inducible chemokine and so on,is expressed by the CCL16 gene located on the chromosome 17 in humans.The gene encodes a 120 a.a.residue precursor protein with a 23 a.a.residue predicted signal peptide that is cleaved to generate a 97 a.a.residue mature protein.The protein is secreted by the liver,thymus,spleen cells and showing chemotactic activity for lymphocytes and monocytes but it is distantly related to other CC chemokines,exhibiting less than 30%sequence identity.CCL16 is highly induced by IL-10,IFN-γ and bacterial lipopolysaccharide in monmcytes and signal through CCR1,CCR2,CCR5,and CCR8.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人LEC/CCL16，LEC/CCL16, Human，Recombinant Human Liver-Expressed Chemokine/CCL16
储存条件：冷冻（-20℃）
概述
Human CCL16,also called Liver-expressed chemokine(LEC),Monotactin-1(MTN-1),IL-10-inducible chemokine and so on,is expressed by the CCL16 gene located on the chromosome 17 in humans.The gene encodes a 120 a.a.residue precursor protein with a 23 a.a.residue predicted signal peptide that is cleaved to generate a 97 a.a.residue mature protein.The protein is secreted by the liver,thymus,spleen cells and showing chemotactic activity for lymphocytes and monocytes but it is distantly related to other CC chemokines,exhibiting less than 30%sequence identity.CCL16 is highly induced by IL-10,IFN-γ and bacterial lipopolysaccharide in monmcytes and signal through CCR1,CCR2,CCR5,and CCR8.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rHuLEC/CCL16 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ |
相关搜索：重组人LEC/CCL16，LEC/CCL16, Human，Recombinant Human Liver-Expressed Chemokine/CCL16